Much of the investigation into Giorgos Mazonakis’s death is now focused on the substances he was allegedly administered before the plasmapheresis, with authorities seeking answers as to exactly what happened during those critical minutes inside the clinic in Kolonaki.

New evidence points to the administration of midazolam to treat intoxication, followed by Anexate as an antidote, while at the same time there are reports that, when the singer had already lost consciousness, the word “propofol” was also heard inside the clinic.

The final answer is expected from the toxicological and histological tests.

The crucial question that investigators must answer is which substance or substances were administered to the singer, in what quantity, and at what time, before the plasmapheresis procedure began.

According to reports, Giorgos Mazonakis was allegedly administered midazolam, a drug belonging to the benzodiazepine class and used for sedation and intoxication.

At the same time, according to the same sources, he was reportedly administered Anexate, i.e., flumazenil, which is a benzodiazepine antagonist.

This detail is considered particularly significant, as flumazenil is used to counteract the sedative effects of drugs such as midazolam, while it is not an antidote for propofol.

However, the presence of Anexate alone is not sufficient to prove exactly which substance was administered, as the entire set of data must be evaluated by the competent authorities.

The Question of Propofol

At the same time, a second piece of evidence leaves open the possibility that another sedative may have been used.

According to information from witness statements, a clinic employee reportedly stated that during the critical moments she heard the words “intoxication” and “propofol.”

Propofol is a potent intravenous anesthetic and sedative used to induce and maintain anesthesia or deeper sedation.

Unlike midazolam, propofol does not have a specific antidote or reversal agent.

This is why the authorities are examining all possibilities: from whether midazolam was used exclusively to whether other substances were administered.

The Nurse’s Two Phone Calls

The two phone calls made by the 56-year-old clinic nurse after 4:00 p.m. carry particular weight in the investigation, as, according to her testimony, an alarm had already been triggered by that time.

She testified for about four hours before the investigating judge and then described what she claims happened that day.

As she stated, the first phone call was made around 4:10–4:15 p.m., at the doctor’s request, to determine whether there was an antidote to propofol.

“Ms. Gaka asked me to find out if there was an antidote for propofol,” she specifically stated.

She claimed that she contacted an anesthesiologist, who told her there was no antidote for propofol, and she then relayed this information to the doctors present at the scene.

The second phone call, according to her testimony, concerned the clinic’s defibrillator, as the device was reportedly not working and instructions on how to use it were requested.

“Everything was going well until four o’clock.”

The nurse described how the situation in the clinic changed around 4:00 p.m.

“Everything was going well until four o’clock,” she said, noting that tension and panic then set in.

As she explained, she remained in an adjacent room where another patient was being treated and had no idea what was happening in the area where Giorgos Mazonakis was located.

She also mentioned that she had seen the singer the previous day, when he had undergone hydrotherapy.

As she explained, his demeanor at that time was different from previous occasions, as “he seemed preoccupied with something.”

At the same time, she clarified that, in her view, the administration of alcohol was not part of the standard procedure for those specific treatments.

Reports on the time of arrival and the location after death

In her testimony, the nurse also referred to what she claims happened after the singer’s death.

She claimed that she was asked to report a different time of Giorgos Mazonakis’s arrival at the clinic.

“He told me to say that specific time—that he arrived around 3:00 or 3:30, even though he had actually arrived at 2:00,” she said.

Regarding the scene after the ambulance crew left, he claimed that tasks were performed which the staff considered part of the standard procedure, such as making the bed and returning the defibrillator to its place.

Regarding the catheters, he stated that one remained in place, while he said he did not know what had happened to the second one.

A Timeline of the Fateful Day

George Mazonakis had visited the clinic on Karneadou Street in Kolonaki on September 9, 2026.

According to the evidence being examined by the authorities, he had undergone hydrotherapy the previous day, after which plasmapheresis was scheduled.

During the procedure, she was reportedly connected to the machine at approximately 2:14 p.m.

At 2:25 p.m., the machine’s first alarm was recorded, and at 2:37 p.m., the blood circulation process began.

A few minutes later, at 2:44 p.m. and 2:45 p.m., the doctor reportedly took a photo of the singer while he was unconscious, which she sent to a colleague.

The machine stopped at 3:22 p.m., while according to the evidence being examined, the singer remained connected for another 23 minutes or so.

At 3:45 p.m., new alerts were recorded, followed by attempts to restart the machine.

The Encounter with the Hypnotherapist and the Change of Plans

The investigation is also examining the role of sleep therapist Nasos Komianos, whom Giorgos Mazonakis had initially contacted seeking help with wellness issues.

According to the evidence being reviewed, the singer had initially considered traveling to London for treatment but ultimately turned to the clinic in Kolonaki.

The two men reportedly came into contact through a mutual associate, and the connection with the doctor was subsequently established.

Messages between the hypnotherapist and the doctor—regarding their communication prior to the singer’s visit to the clinic—have also come under scrutiny.

The Family’s Position

The family of Giorgos Mazonakis has requested that the toxicology tests be expedited in order to determine the exact cause of death.

The family’s attorney, Charalambos Lykoudis, has expressed reservations about the nurse’s testimony, arguing that certain points align with the doctor’s defense.

At the same time, he has left open the possibility that new suspects or new charges may emerge from the investigation.

Source: Protothema.gr